Methyl magnesium bromide
Agent Name
Methyl magnesium bromide
CAS Number
75-16-1
Formula
C-H3-Br-Mg
Major Category
Metals
Synonyms
Bromomethylmagnesium; Magnesium, bromomethyl-; Magnesium, methyl-, bromide (ethyl ether solution); Methylmagnesium bromide; Methyl magnesium bromide, in ethyl ether; [ChemIDplus] UN1928
Category
Metals, Organic Compounds
Description
Diethyl ether solution: Cloudy colorless liquid; [CAMEO] In 1.4m toluene/tetrahydrofuran solution: Orange liquid; [MSDSonline]
Sources/Uses
Used as alkylating agent in organic synthesis and as a Grignard reagent; [HSDB]
Comments
May have violent reaction with water; [HSDB] A strong reducing agent that is highly flammable; Reacts with water evolving methane; May form unstable peroxides on contact with air; [CAMEO] "Apart from their instability in air and their caustic basic properties, organomagnesium compounds and the precipitated inorganic magnesium salts produced during their use display no pronounced toxicity or side effects of environmental concern." [Ullmann] Reacts violently with water; May form explosive peroxides; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis and pulmonary edema; Inhalation of high concentrations can cause CNS depression; [MSDSonline]
Biomedical References
Exposure Assessment
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Methyl magnesium bromide in Ethyl ether;
Adverse Effects
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.