Muscarine chloride
Agent Name
Muscarine chloride
CAS Number
2303-35-7
Formula
C9-H20-N-O2.Cl
Major Category
Biological Agents
Synonyms
(+)-Muscarine chloride; 2-Furanmethanaminium, tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-, chloride, (2S-(2alpha,4beta,5alpha))-; L-(+)-Muscarine chloride; [ChemIDplus]
Category
Mushroom Toxins
Description
Extremely hygroscopic solid; [Merck Index]
Sources/Uses
Muscarine: Alkaloid found in red variety of Amanita muscaria and other fungi; Used as a cholinergic drug; [Merck Index] Used strictly for research purposes; [HSDB]
Comments
Intravenous LD50 (mouse) = 230 ug/kg; [RTECS] Emergency treatment: "Mushrooms- muscarine/histamine"; Used in research because it causes excitatory effects on cells innervated by postganglionic cholinergic nerves, but none on nicotinic receptors of autonomic ganglia or skeletal muscles; [HSDB] Symptoms after ingestion are sweating, salivation, impaired vision, nausea, vomiting, abdominal pain, diarrhea, headache, and bronchospasm; High doses may cause lacrimation, incontinence, bradycardia, hypotension, and shock; [Merck Index] May cause irritation; Highly toxic by inhalation, skin absorption, and ingestion; Targets nerves; [MSDSonline]
Reference Link #1
Biomedical References
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.