Muscimol
Agent Name
Muscimol
CAS Number
2763-96-4
Formula
C4-H6-N2-O2
Major Category
Biological Agents
Synonyms
3(2H)-Isoxazolone, 5-(aminomethyl)-; 3-Hydroxy-5-aminomethylisoxazole; 3-Isoxazolol, 5-(aminomethyl)-; 5-(Aminomethyl)-3(2H)-isoxazolone; 5-(Aminomethyl)-3-isoxazolol; 5-Aminomethyl-3-hydroxyisoxazole; 5-Aminomethyl-3-isoxyzole; Agarin; Agarine; Pantherin; Pantherine; [ChemIDplus]
Category
Mushroom Toxins
Description
Solid; [Merck Index] White powder; [MSDSonline]
Sources/Uses
Isolated from Amanita muscaria; Used to study GABA receptors; [Merck Index] Used in studies of GABA-A receptors; [ChemIDplus]
Comments
Causes somnolence and rigidity in rat experiments; In humans (route not reported), caused sleep, hallucinations, nausea, and vomiting; [RTECS] A strong CNS depressant; A GABA agonist; [Merck Index] May cause irritation and CNS depression; May cause neurotoxic effects and convulsions; [MSDSonline]
Reference Link #1
Biomedical References
Exposure Assessment
Vapor Pressure
0.000294 mm Hg
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.