N-Methyl-N'-nitro-N-nitrosoguanidine

Agent Name
N-Methyl-N'-nitro-N-nitrosoguanidine
CAS Number
70-25-7
Formula
C2-H5-N5-O3
Major Category
Nitrogen Compounds
N-Methyl-N'-nitro-N-nitrosoguanidine formula graphical representation
Synonyms
1-Methyl-1-nitroso-3-nitroguanidine; 1-Methyl-3-nitro-1-nitrosoguanidine; 1-Nitroso-3-nitro-1-methylguanidine; Guanidine, 1-methyl-3-nitro-1-nitroso-; Guanidine, N-methyl-N'-nitro-N-nitroso-; MNG; MNNG; Methylnitronitrosoguanidine; N'-Nitro-N-nitroso-N-methylguanidine; N-Methyl-N'-nitro-N-nitrosoguanidine; N-Methyl-N-nitroso-N'-nitroguanidine; N-Methyl-N-nitrosonitroguanidin [German]; N-Methylo-N'-nitro-N-nitrozoguanidyny [Polish]; N-Metylo-N'-nitro-N-nitrozoguanidyny [Polish]; N-Nitroso-N'-nitro-N-methylguanidine; N-Nitroso-N-methyl-N'-nitroguanidine; N-Nitroso-N-methylnitroguanidine; [ChemIDplus] UN1325
Category
Other Nitrogen Compounds
Description
Yellow solid; [Merck Index] Pale yellow to pink solid; Light sensitive, changes color to orange and green; [HSDB] Yellow crystals; [Aldrich MSDS]
Sources/Uses
Used as experimental carcinogen and mutagen; Used formerly to make diazomethane; [Merck Index]
Comments
Mutagenic to human cells; No expected human exposure outside of laboratories where it is used for research; Evidence of carcinogenicity and mutagenicity in experimental animals; [HSDB] Highly flammable, explosive, and violently reactive with water; [CAMEO] A skin and eye irritant; [eChemPortal: ESIS] Toxic to embryonic development in experimental animals; ]REPROTOX] Causes convulsions, acute pulmonary edema, and ulceration or bleeding from stomach in oral lethal-dose studies of rats; Causes changes to liver, GI tract, blood, and lipids in oral toxic-dose studies of mice; [RTECS] An irritant; [Aldrich MSDS]
Biomedical References

Exposure Assessment

Vapor Pressure
0.00012 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Flammable solid, organic, n.o.s." VP from ChemIDplus;

Adverse Effects

Neurotoxin
Other CNS neurotoxin
Reproductive Toxin
Yes
IARC Carcinogen
Probable (2a)
NTP Carcinogen
Anticipated human carcinogen

Diseases, Processes, and Activities Linked to This Agent

Other Information
No other related information on this agent was found.