Nicarbazin

Agent Name
Nicarbazin
CAS Number
330-95-0
Formula
C13-H10-N4-O5.C6-H8-N2-O
Major Category
Other Uses
Nicarbazin formula graphical representation
Synonyms
4,4'-Dinitrocarbanilide, compd. with 4,6-dimethyl-2-pyrimidinol; MK 75; MK 75 (VAN); N,N'-Bis(4-nitrophenyl)urea compd. with 4,6-dimethyl-2-pyrimidinol (1:1); Nicarb; Nicarbasin; Nicarbazine; Nicoxin; Nicrazin; Nicrazine; Nirazin; 1,3-Bis(4-nitrophenyl)urea-4,6-dimethylpyrimidin-2-ol; Carbanilide, 4,4'-dinitro-, compd. with 4,6-dimethyl-2-pyrimidinol (1:1); Urea, N,N'-bis(4-nitrophenyl)-, compd. with 4,6-dimethyl-2(1H)-pyrimidinone (1:1); [ChemIDplus]
Category
Animal Feed Additives
Description
Light yellow solid; [HSDB]
Sources/Uses
Used as a coccidiostat for poultry and to reduce egg hatching in resident Canadian geese; [HSDB]
Comments
An equimolar complex of 4,4'-dinitrocarbanilide and 2-hydroxy-4,6-dimethylprimidine; A moderate eye irritant; Oral LD50 (rat) >10,000 mg/kg; In high-dose feeding studies of dogs over 2 years, it caused liver injury in doses >240 mg/kg/day; In another animal study, the NOEL for maternal and fetal toxicity was 200 mg/kg/day; [HSDB] An irritant; [MSDSonline]
Reference Link #1
Biomedical References

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: