N,N'-Di-sec-butyl-p-phenylenediamine

Synonyms

1,4-Benzenediamine, N,N'-bis(1-methylpropyl)-; Antioxidant 22; Du Pont Gasoline Antioxidant No. 22; Kerobit BPD; N,N'-Di-s-butyl-p-phenylenediamine; N,N'-Di-sec-butyl-p-phenyldiamine; N,N'-Di-sec-butylparaphenylenediamine; N,N'-Di-sek.butyl-p-fenylendiamin [Czech]; Santoflex 44; Tenamene 2; Topanol M; UOP 5; p-Phenylenediamine, N,N'-di-sec-butyl-; [ChemIDplus] UN2922

Category

Amines, Aromatic

Description

Pale yellow or amber to red liquid; mp = 18 deg C; [HSDB] Dark red liquid; [MSDSonline]

Sources/Uses

Used in gasoline (gum inhibitor, antioxidant, and stabilizer) and styrene-butadiene rubbers (antioxidant and antiozonant); [HSDB]

Comments

Emergency treatment: "Paraphenylenediamine"; In sensitized individuals, paraphenylenediamine may cause allergic contact dermatitis following application as a hair dye and asthma following inhalation; Following ingestion, can cause angioneurotic edema, methemoglobinemia, acute tubular necrosis, and hepatotoxicity; An adult died after ingestion of 3 grams of p-phenylenediamine; Another adult who ingested 1800 mg developed angioneurotic edema and acute renal failure; [HSDB] A strong irritant that may cause burns; [CAMEO] Highly irritating or corrosive to skin and eyes, based on animal studies; [eChemPortal: HPVIS] Causes burns; May cause skin sensitization; Toxic if swallowed; Absorbed through skin; [Aldrich MSDS] See "p-Phenylenediamine."

Biomedical References

0.00156 mm Hg

LCLo (rat) = 600 mg/m3/6h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Corrosive liquid, toxic, n.o.s." VP from ChemIDplus;

high ambient temp required

Yes

MetHgb is secondary toxic effect

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Skin burns

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Petroleum Production and Refining