Sulfur difluoride dioxide; Vikane®; [NIOSH] UN2191
Colorless, odorless gas. [insecticide/fumigant] [Note: Shipped as a liquefied compressed gas.] [NIOSH]
Used as a structural fumigant to kill termites; [ACGIH]
Concentrations inside fumigated structures are as high as 4000 to 40,000 ppm. Inhalation exposure may cause pulmonary edema. [ACGIH] Because sulfuryl fluoride is heavier than air, workers who re-enter a treated area are at risk for fatal hypoxia. Muscle twitching and seizures have been reported after acute poisoning. [EPA Pesticides, p. 161] Possible frostbite from contact with liquid; [NIOSH] The exact toxic mechanism is not known, but increased fluoride ion concentrations have been found in poisoned victims. Systemic fluorosis may result from sulfuryl fluoride poisoning. Fluoride can cause hypocalcemia and hyperkalemia with secondary arrhythmias and central nervous effects including agitation, tetany, and seizures. [AHLS, p. 266-7] This gas has no warning properties, but chloropicrin is often added. After chronic inhalation studies, animals have evidence of liver injury. [HSDB] See "FLUORIDES."
Skin Designation (ACGIH)
Excerpts from Documentation for IDLHs
Other animal data: It has been reported that less than 5% mortality resulted from exposure for 3 hours to 1,000 ppm [Taxay 1966].
LC50 (rat) = 991 ppm/4H
Not combustible; [CHEMINFO]
Other CNS neurotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Occupational diseases associated with exposure to this agent:
Industrial Processes with risk of exposure: