o-Nitroanisole
Agent Name
o-Nitroanisole
Alternative Name
2-Nitroanisole
CAS Number
91-23-6
Formula
C7-H7-N-O3
Major Category
Nitrogen Compounds
Synonyms
1-Methoxy-2-nitrobenzene; 1-Nitro-2-methoxybenzene; 2-Methoxy-1-nitrobenzene; 2-Methoxynitrobenzene; 2-Nitroanisole; Anisole, o-nitro-; Benzene, 1-methoxy-2-nitro-; o-Nitrophenyl methyl ether; ortho-Nitrobenzene methyl ether; [ChemIDplus] UN2730
Category
Other Aromatics (Nitrogen)
Description
Colorless, yellow, or reddish liquid; [HSDB] Yellow liquid; mp = 9-10 deg C; [MSDSonline]
Sources/Uses
Used in organic synthesis to produce pharmaceuticals and dyes; [Hawley]
Comments
Inhalation of high concentrations can cause methemoglobinemia; "The substance may have effects on the blood, resulting in anaemia." [ICSC] An irritant; Effects in high-dose animal studies include methemoglobinemia; [MSDSonline] See 2021 (Volume 127) monograph at IARC.
Biomedical References
Exposure Assessment
Vapor Pressure
0.0036 mm Hg
Explanatory Notes
Flash point = 124 deg C; [ICSC] The Guide in the Emergency Response Guidebook is for "Nitroanisoles, liquid." VP from ChemIDplus;
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
IARC Carcinogen
Probable (2a)
NTP Carcinogen
Anticipated human carcinogen
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.