Octinoxate

Synonyms

2-Ethylhexyl methoxycinnamate; 2-Ethylhexyl-4-methoxycinnamate; 3-(4-Methoxyphenyl)-2-propenoic acid, 2-ethylhexyl ester; Octyl methoxycinnamate; 2-Ethylhexyl p-methoxycinnamate; 2-Propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester; Escalol; Neo Heliopan; Parsol MOX; [ChemIDplus]

Category

Sunscreens

Description

Colorless to pale yellow liquid; [CAMEO] Pale yellow liquid; [MSDSonline]

Sources/Uses

Used as ultraviolet sunscreen; [Merck Index]

Comments

May cause photoallergic contact dermatitis in certain individuals; [HSDB] It is patch tested at 7.5% concentration in petrolatum; It is a very low-level sensitizer: 1/108 patients tested photo-patch test positive; In another series, 1/280 and 1/280 tested positive for patch or photo patch, respectively; Octinoxate may be found in cosmetics, shampoos, and lip balms; [Marks, p. 219] May cause photosensitivity and irritation; [MSDSonline]

Biomedical References

1.4E-05 mm Hg

Yes

PACD (photoallergic contact dermatitis)

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Contact dermatitis, photoallergic