Octabenzone

Agent Name
Octabenzone
CAS Number
1843-05-6
Formula
C21-H26-O3
Major Category
Other Uses
Octabenzone formula graphical representation
Synonyms
(2-Hydroxy-4-(octyloxy)phenyl)phenylmethanone; 2-Benzoyl-5-octyloxyphenol; 2-Hydorxy-4-octoxybenzophenone; 2-Hydroxy-4-(n-octoxy)benzophenone; 2-Hydroxy-4-(n-octyloxy)benzophenone; 2-Hydroxy-4-(octyloxy)benzophenon; 2-Hydroxy-4-(octyloxy)benzophenone; 2-Hydroxy-4-octoxybenzophenone; 2-Hydroxy-4-octyloxybenzophenone; 2-Hydroxy-4-oktyloxybenzofenon [Czech]; 4-(Octyloxy)-2-hydroxybenzophenone; 4-Octoxy-2-hydroxybenzophenone; 4-n-Octyloxy-2-hydroxybenzophenone; Aduvex 248; Advastab 46; Anti-UV P; Benzon OO; Benzophenone 12; Benzophenone, 2-hydroxy-4-(octyloxy)-; Biosorb 130; Carstab 700; Chimassorb 81; Cyasorb UV 531; Mark 1413; Methanone, (2-hydroxy-4-(octyloxy)phenyl)phenyl-; Octabenzona [INN-Spanish]; Octabenzonum [INN-Latin]; Rhodialux P; Sanduvor 3035; Seikalizer E; Spectra-Sorb UV 531; Sumisorb 130; UF 4; UNII-73P3618V2E; UV 1; UV 1 (ultroviolet absorber); UV 531; UVA 1; Uvinul 408; Uvinul M 408; Viosorb 130; Zislizer E; 2-Hydroxy-4-n-octyloxybenzophenone; [ChemIDplus]
Category
Sunscreens
Description
Colorless solid; [Hawley] Light yellow solid; [MSDSonline]
Sources/Uses
Used as an ultraviolet stabilizer for polyethylene and an ultraviolet sunscreen; [Merck Index]
Comments
Not irritating to skin or eyes of rabbits; Caused skin sensitization in a guinea pig study; [IUCLID] Oral LD50 (rat) >10,000 mg/kg; [ChemIDplus] Caused skin sensitization in guinea pig maximization test (60-78% positive), but not in human patch test study involving 50 people; Effects in high-dose animal studies (rats) include kidney injury; [MSDSonline] See "Oxybenzone."
Biomedical References

Exposure Assessment

Adverse Effects

Skin Sensitizer
Yes
Dermatotoxin
PACD (photoallergic contact dermatitis)

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: