N,N-Dimethyl-N-dodecylamine oxide

Synonyms

Lauramine oxide; Lauryl dimethyl amine oxide; N,N-Dimethyl-1-dodecanamine-N-oxide; 1-Dodecanamine, N,N-dimethyl-, N-oxide; Ammonyx AO; Ammonyx LO; Amonyx AO; Aromox DMCD; Aromox dmmc-W; Conco XAL; DDNO; Dimethylaurylamine oxide; Dimethyldodecylamine N-oxide; Dimethyldodecylamine oxide; Dimethyllaurylamine oxide; Dodecylamine, N,N-dimethyl-, N-oxide; Dodecyldimethylamine N-oxide; Dodecyldimethylamine oxide; Empigen OB; Lauryldimethylamine N-oxide; Lauryldimethylamine oxide; N,N-Dimethyl-dodecylaminoxid [Czech]; N,N-Dimethyldodecylamine oxide; N-Lauryl-N,N-dimethylamine oxide; N-Lauryldimethylamine N-oxide; Oxyde de dimethyllaurylamine [French]; Refan [Russian]; n-Dodecyldimethylamine oxide; [ChemIDplus] UN3259

Category

Emulsifiers/Surfactants

Description

Highly hygroscopic solid; [HSDB]

Sources/Uses

Used as a foam builder and stabilizer; Used in cosmetics, emollients, conditioners, emulsifiers, dishwasher detergents, shampoos, soaps, and antistatic, wetting, antibacterial, and antifungal agents; [HSDB]

Comments

Caused severe skin irritation (including severe erythema and edema, fissuring with bleeding, and necrosis) in rabbit studies; High dose animal feeding studies produced no significant adverse effects; [HSDB] Amine oxides are metabolized and rapidly excreted after ingestion; Effects on skin are: 1% solutions not irritating, 5% solutions moderately irritating, and 30% solutions severely irritating; No evidence of skin sensitization; No evidence of carcinogenic response or reproductive toxicity; [OECD SIDS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]

Biomedical References

6.23E-08 mm Hg

LC50 (rat) = 5.3 g/mL/4h (aerosol of 0.3% lauramine oxide;

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Amines, solid, corrosive, n.o.s."

Yes

Skin burns

Processes

Industrial Processes with risk of exposure:

• Using Disinfectants or Biocides