Tetrachloronaphthalene

Agent Name
Tetrachloronaphthalene
CAS Number
1335-88-2
Formula
C10-H4-Cl4
Major Category
Other Classes
Tetrachloronaphthalene formula graphical representation
Synonyms
Halowax; Nibren wax; Seekay wax; [NIOSH]
Category
Halowaxes
Description
Colorless to pale-yellow solid with an aromatic odor; [NIOSH]
Sources/Uses
"There are no known commercial uses for purified individual isomers of di-, tri-, tetra-, penta-, hexa-, or heptachloronaphthalene." [HSDB]
Comments
Chlorinated naphthalenes may be absorbed through the skin. They cause liver injury and hyperkeratosis in experimental animals. Penta- and hexachloronaphthalene may cause in exposed workers acne-like lesions that itch severely. Tri-, tetra-, and octachloronaphthalene are non-acnegenic under the conditions of industrial use. Nine occupational fatalities from chlorinated naphthalene poisoning have been reported. Most cases of intoxication among cable workers, assemblers, and laborers involve either penta- or hexachloronaphthalene. A nonfatal case of toxic hepatitis was reported in an 18 year old female who was soldering electrical condensers. [ACGIH] Acne-form dermatitis is listed as an adverse effect for all of the halowaxes except trichloronaphthalene in the NIOSH Pocket Guide. May cause liver injury; [ICSC]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
Bioaccumulates
Yes
TLV (ACGIH)
2 mg/m3
PEL (OSHA)
2 mg/m3
Excerpts from Documentation for IDLHs
Animal data: It has been stated that tetrachloronaphthalene has been shown to be less toxic to the liver than more highly chlorinated derivatives of naphthalene [ACGIH 1986]. . . . Basis for revised IDLH: Due to a lack of relevant acute toxicity data, the IDLH for tetrachloronaphthalene remains "Unknown."
Vapor Pressure
1E-06 mm Hg
Explanatory Notes
Flash point = 210 deg C;

Adverse Effects

Hepatotoxin
Occupational hepatotoxin (principal effect)
Dermatotoxin
Chloracne

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: