4-Chloroacetophenone

Agent Name
4-Chloroacetophenone
CAS Number
99-91-2
Formula
C8-H7-Cl-O
Major Category
Other Classes
4-Chloroacetophenone formula graphical representation
Synonyms
1-(4-Chlorophenyl)ethanone; 4'-Chloroacetophenone; 4-Acetylchlorobenzene; 4-Chlorophenyl methyl ketone; Acetophenone, 4'-chloro-; Ethanone, 1-(4-chlorophenyl)-; Methyl 4-chlorophenyl ketone; Methyl p-chlorophenyl ketone; p-Acetylchlorobenzene; p-Chloracetophenone; p-Chloroacetophenone; p-Chlorophenyl methyl ketone; [ChemIDplus] UN1697
Category
Aromatic Ketones, Halogenated
Description
Liquid; [Merck Index] Colorless liquid; [MSDSonline]
Sources/Uses
Used as a chemical intermediate for pharmaceuticals; [HSDB]
Comments
"Highly irritating to eyes"; [Merck Index] May cause allergic contact dermatitis; [HSDB] An irritant; Effects in high-dose animal studies include lacrimation and acute pulmonary edema; [MSDSonline] See "alpha-Chloroacetophenone."
Biomedical References
Search PubMed

Exposure Assessment

Vapor Pressure
0.122 mm Hg
Lethal Concentration
LC50 (mice) = 1,752 mg/m3/15min
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Chloroacetophenone, liquid." VP from ChemIDplus;

Adverse Effects

Skin Sensitizer
Yes
Toxic Pneumonitis
Yes

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: