Santonox

Synonyms

4,4`-Thiobis-(6-tert-butyl-m-cresol); 1,1'-Thiobis(2-methyl-4-hydroxy-5-tert-butylbenzene); 4,4'-Thiobis(2-(1,1-dimethylethyl)-5-methylphenol); 4,4'-Thiobis(2-tert-butyl-5-methylphenol); 4,4'-Thiobis(3-methyl-6-tert-butylphenol); 4,4'-Thiobis(6-tert-butyl-3-methylphenol); 4,4'-Thiobis(6-tert-butyl-m-cresol); Antage Crystal; Antioxidant AO; Antioxidant TMB 6; Bis(3-tert-butyl-4-hydroxy-6-methylphenyl) sulfide; Bis(4-hydroxy-5-tert-butyl-2-methylphenyl) sulfide; Disperse MB-61; Nocrac 300; Nonflex BPS; Santonox; Santonox BM; Santonox R; Santowhite crystals; Santox; Sumilizer WX; Sumilizer WX-R; Thioalkofen BM 4; Thioalkofen BMCH; Thioalkofen MBCH; Thioalkophene BM-4; Yoshinox S; Yoshinox SR; [ChemIDplus]

Category

Curing Agents (Aromatic)

Description

Light-gray to tan powder with a slightly aromatic odor; [NIOSH]

Sources/Uses

Used as an antioxidant in the manufacturing of synthetic rubber and plastics; [HSDB]

Comments

Liver toxicity observed in 2-year feeding studies of rodents; Two patients had positive patch tests after developing contact dermatitis from latex gloves containing Santonox, but this was not confirmed in three other studies that found no evidence of skin sensitization; TLV Basis is respiratory tract irritation; [ACGIH] A skin, eye, and respiratory tract irritant; [CAMEO]

Biomedical References

No

1 mg/m3, Inhalable particulate matter

15 mg/m3(total dust), 5 mg/m3(respirable fraction)

Explanatory Notes

Flash point = 420 deg F; VP from Cameo = 0.0000006 @ 158 deg F;

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Not Classifiable

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing