Perfluorooctylsulfonyl fluoride
Agent Name
Perfluorooctylsulfonyl fluoride
Alternative Name
POSF
CAS Number
307-35-7
Formula
C8-F18-O2-S
Major Category
Other Classes
Synonyms
POSF; 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluoro-1-octanesulfonyl fluoride; 1-Octanesulfonyl fluoride, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-; N-Perfluorooctanesulfonyl fluoride; Perfluorooctanesulfonyl fluoride; Heptadecafluorooctanesulphonyl fluoride; [ChemIDplus] POSF; [EPA]
Category
Other Organic Compounds
Description
Clear liquid; [MSDSonline]
Sources/Uses
Used as a precursor for various perfluorinated amides, alcohols, acrylates, and other fluorochemical polymers; [EPA]
Comments
Emergency treatment: "Fluoride"; [HSDB] Repeated high-dose studies have shown the liver to be the primary target organ; Effects observed in reproductive studies include increase in neonatal mortality; Multi-generational studies showed no effects to post-natal neurological development or to fertility in offspring; No evidence of mutagenicity; Perfluorooctanesulfonyl fluoride (POSF) based fluorochemicals can be absorbed into the body and metabolized into perfluorooctanesulfonate (PFOS); Monitoring of PFOS has been used to measure employee exposure to POSF based chemicals in manufacturing; [EPA] See "Perfluorooctane sulfonic acid."
Biomedical References
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.