1,2,4-Trichlorobenzene

Agent Name
1,2,4-Trichlorobenzene
CAS Number
120-82-1
Formula
C6-H3-Cl3
Major Category
Solvents
1,2,4-Trichlorobenzene formula graphical representation
Synonyms
1,2,4-Trichlorobenzene; 1,2,4-Trichlorobenzol; 1,3,4-Trichlorobenzene; Hostetex L-pec; Trojchlorobenzen [Polish]; unsym-Trichlorobenzene; [ChemIDplus] UN2321
Category
Chlorinated Aromatics
Description
Colorless liquid or crystalline solid (below 63 degrees F) with an aromatic odor; [NIOSH]
Sources/Uses
Used as a dielectric and heat transfer fluid and as an intermediate for other organic chemicals; [ACGIH] Used as a degreaser, wood preservative, and dye solvent; [HSDB]
Comments
Animal studies show 1,2,4-trichlorobenzene to be toxic to the liver, kidneys, and brain (central nervous system depressant). [ACGIH] A skin, eye, and respiratory tract irritant; May cause liver injury; [ICSC]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
Ceiling (ACGIH)
5 ppm
MAK
0.5 ppm
Vapor Pressure
0.46 mm Hg
Odor Threshold Low
2.96 ppm
Explanatory Notes
Odor threshold from AIHA; Flash point = 105 deg C; VP from HSDB;
NFPA
must be preheated

Adverse Effects

Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: