1,2,4-Trichlorobenzene

Synonyms

1,2,4-Trichlorobenzene; 1,2,4-Trichlorobenzol; 1,3,4-Trichlorobenzene; Hostetex L-pec; Trojchlorobenzen [Polish]; unsym-Trichlorobenzene; [ChemIDplus] UN2321

Category

Chlorinated Aromatics

Description

Colorless liquid or crystalline solid (below 63 degrees F) with an aromatic odor; [NIOSH]

Sources/Uses

Used as a dielectric and heat transfer fluid and as an intermediate for other organic chemicals; [ACGIH] Used as a degreaser, wood preservative, and dye solvent; [HSDB]

Comments

Animal studies show 1,2,4-trichlorobenzene to be toxic to the liver, kidneys, and brain (central nervous system depressant). [ACGIH] A skin, eye, and respiratory tract irritant; May cause liver injury; [ICSC]

Biomedical References

Insufficient data

5 ppm

0.5 ppm

0.46 mm Hg

2.96 ppm

Explanatory Notes

Odor threshold from AIHA; Flash point = 105 deg C; VP from HSDB;

must be preheated

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Applying Wood Preservatives
• Metal Degreasing