1,1,2-Trichloro-1,2,2-trifluoroethane

Agent Name
1,1,2-Trichloro-1,2,2-trifluoroethane
CAS Number
76-13-1
Formula
C2-Cl3-F3
Major Category
Solvents
Synonyms
1,1,2-Trichlorotrifluoroethane; 1,1,2-Trifluoro-1,2,2-trichloroethane; 1,1,2-Trifluorotrichloroethane; 1,2,2-Trichlorotrifluoroethane; Arcton 63; Arklone P; Asahifron 113; CFC-113; Chlorofluorocarbon 113; Daiflon S 3; Ethane, 1,1,2-trichloro-1,2,2-trifluoro-; F 113; FC 113; Flugene 113; Fluorocarbon 113; Forane 113; Freon 113; Freon 113TR-T; Freon F113; Freon R 113; Freon TF; Frigen 113; Frigen 113 TR-T; Frigen 113A; Frigen 113TR; Frigen 113TR-N; Frigen 113tr-T; Genesolv D; Genetron 113; Halocarbon 113; Isceon 113; Kaiser chemicals 11; Kaltron 113MDR; Khladon 113; Ledon 113; Propellant 113; R 113; R 113 (Halocarbon); Racon 113; Refrigerant 113; Refrigerant R 113; Trichlorotrifluoroethane; Ucon fluorocarbon 113; [ChemIDplus]
Category
Chlorofluorocarbons
Description
Colorless to water-white liquid with an odor like carbon tetrachloride at high concentrations. [Note: A gas above 118 degrees F.]; [NIOSH]
Sources/Uses
CFC-113 has been used as s solvent (degreasing and dry cleaning), refrigerant, heat transfer liquid, and chemical intermediate; [ACGIH]
Comments
A weak narcotic and strong cardiac sensitizer compared to other CFCs; In animal experiments, CNS depression occurs with exposures above 12,000 ppm; Mild liver changes are noted at concentrations somewhat below this; [ACGIH] Inhalation of high concentrations can cause CNS depression and cardiac arrhythmias; In confined space spill, may displace air and act as simple asphyxiant; An eye irritant; [ICSC]
Restricted
See CHLOROFLUOROCARBONS
Biomedical References
Search PubMed

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
1000 ppm
STEL (ACGIH)
1250 ppm
PEL (OSHA)
1000 ppm
MAK
500 ppm
IDLH (NIOSH)
2000 ppm
Excerpts from Documentation for IDLHs
Human data: Human volunteers exposed to 2,500 ppm had subjective symptoms of diminished concentration, somnolence, and head heaviness within 30 minutes of initiation of exposure and slight but definite further significant decrements at exposures for 2.75 hours at 4,500 ppm [Stopps and McLaughlin 1967]. No adverse changes were noted in volunteers exposed to 500 or 1,000 ppm for 6 hours per day, 5 days per week for 2 weeks [Reinhardt et al. 1971].
Vapor Pressure
363 mm Hg
Odor Threshold Low
45 ppm
Odor Threshold High
70 ppm
Lethal Concentration
LC50 (rat) = 38,500 ppm/4H
Explanatory Notes
Odor thresholds (detection at 45 ppm and recognition at 70 ppm) from CHEMINFO; VP from HSDB;

Adverse Effects

Neurotoxin
Acute solvent syndrome
ACGIH Carcinogen
Not Classifiable

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: