Tri-m-cresyl phosphate
Agent Name
Tri-m-cresyl phosphate
Alternative Name
Trimetacresyl phosphate
CAS Number
563-04-2
Formula
C21-H21-O4-P
Major Category
Other Classes
Synonyms
Phosphoric acid tri-m-tolyl ester; Phosphoric acid, tri(3-tolyl)ester; Phosphoric acid, tris(3-methylphenyl) ester; Tri-m-tolyl phosphate; Tris(m-tolyl) phosphate; Tris-m-cresyl phosphate; [ChemIDplus] UN2574
Category
Organophosphates, Other
Description
Wax; mp = 25.5 deg C; [HSDB] Slightly yellow to pink clear liquid; [MSDSonline]
Sources/Uses
Used in a isomeric mixture known as Tricresyl phosphate (CAS # 1330-78-5); No uses for the isolated isomer; [HSDB]
Comments
Permanent paralysis reported in worker involved in manufacture of meta and para isomers; Mildly toxic to animals; Six times less toxic than the ortho isomer; Emergency treatment: "TOCP and related agents"; [HSDB] A metabolite of the ortho isomer (TOCP) caused "ginger jake paralysis," a motor neuropathy. See "Triorthocresyl phosphate," Tri-p-cresyl phosphate," and "Tricresyl phosphate (mixed isomers)." TLV Basis includes adrenal gland and female reproductive system damage. [ACGIH TLVs and BEIs]
Biomedical References
Exposure Assessment
Vapor Pressure
1.09E-07 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Tricesyl phosphate."
Adverse Effects
Reproductive Toxin
Yes
Other Poison
Organophosphate
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: