Polyphosphoric acid

Agent Name
Polyphosphoric acid
CAS Number
Major Category
Toxic Gases & Vapors
Condensed phosphoric acid; Phospholeum; Polyphosphoric acids; Superphosphoric acid; [ChemIDplus]
Acids, Inorganic
Water-white hygroscopic liquid; [Hawley] Colorless hygroscopic liquid; [HSDB]
A series of strong phosphoric acids with the equation H(2n) P(n) O(3n+1); For pyrophosphoric acid (H4P2O7), n=2; Commercial product is a mixture of these acids and sold based on percentage H3PO4; Used as dehydrating, catalytic, and sequestering agents, for metal treatment, and as laboratory reagents; [Hawley] Used as protein precipitants (for coagulation, separation, and purification), catalysts (petroleum and chemical industries), dehydrating agents (dye and pigment production), and stabilizers (skimmed sweetened condensed milk and dry milk); Also used to make phosphate esters and fertilizers; [HSDB]
Emergency treatment: "Phosphoric acid"; Concentrations of phosphoric acid >75% cause severe burns and can produce phosphine gas after reacting with metal; Ingestion of as little as 8 mL of phosphoric acid can be fatal; [HSDB] A corrosive substance that can cause injury to the skin and eyes; Mists can cause severe irritation to nose, throat, and respiratory tract; [CHEMINFO] Corrosive to skin and eyes; After inhalation, may cause acute pneumonitis; May cause injury to liver and bone; [Alfa Aesar MSDS]
Biomedical References

Adverse Effects

Toxic Pneumonitis
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Skin burns

Diseases, Processes, and Activities Linked to This Agent


Industrial Processes with risk of exposure: