Dimethylaminopropionitrile
Agent Name
Dimethylaminopropionitrile
CAS Number
1738-25-6
Formula
C5-H10-N2
Major Category
Nitrogen Compounds
Synonyms
3-(Dimethylamino)propanenitrile; 3-(Dimethylamino)propionitrile; 3-(N,N-Dimethylamino)propionitrile; 3-Dimethylaminopropannitril [Czech]; Dmapn; N,N-(Dimethylamino)-3-propionitrile; Propanenitrile, 3-(dimethylamino)-; Propionitrile, 3-(dimethylamino)-; beta-(N-Dimethylamino)propionitrile; beta-Dimethylaminopropionitrile; [ChemIDplus]
Category
Nitriles
Description
Colorless liquid; [NIOSH]
Sources/Uses
Dimethylaminopropionitrile was a component of catalysts used in manufacture of flexible polyurethane foams. [LaDou, p. 500]
Comments
Workers at polyurethane production plants developed neurogenic bladder dysfunction after exposure to the catalyst. [LaDou, p. 500] "A skin and eye irritant."; [HSDB] Symptoms of workers included erectile dysfunction and urinary retention. Cystometrograms confirmed neurogenic bladder. In follow-up studies 2 years later, 11 workers were still symptomatic with bladder and sexual dysfunction. A smaller group still had evidence of sensory neuropathy. [Rom, p. 644] See "NIAX catalyst ESN." See ""Propionitrile."
Restricted
Production of catalysts containing this chemical was discontinued after 1978; [Ladou, p. 500]
Biomedical References
Exposure Assessment
Explanatory Notes
VP = 10 mmHg @ 135 degrees F; Flash point = 147 deg F;
NFPA
high ambient temp required
Adverse Effects
Neurotoxin
Sensorimotor
Other Poison
Chemical Asphyxiant
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.