Spinosyn A

Synonyms

(-)-Spinosyn A; (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-2-((6-Deoxy-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy)-13-(((2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-9-ethyl-14-methyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-1H-as-indaceno(3,2-d)oxacyclododecin-7,15-dione; LY-232105; Lepicidin A; PP-105; Spinosad factor A; Spinosyn-A; [ChemIDplus]

Category

Other Insecticides

Description

White odorless solid; [Merck Index]

Sources/Uses

Spinosyns: Macrocyclic lactones derived from fermentation; More than twenty have been isolated from Saccharopolyspora spinosa (soil bacterium); Used as an insecticide; [Merck Index] Used to control tobacco budworm, cotton bollworm, cotton leafperforator, European corn borer, armyworms, loopers, saltmarsh caterpillar, and thrips; [Reference #1] Spinosad contains about 80% spinosyn A and 20% spinosyn D plus traces of structurally related components; [Krieger, p. 162]

Comments

Spinosad has a half-life of about 2 weeks in soil; it retains insecticidal activity indoors for 9-12 months in stored tobacco or wheat; No human poisoning cases reported; [Krieger, p. 163]

Reference Link #1

Biomedical References

2.25E-10 mm Hg

LC50 (rat) > 499 mg/m3/4h

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)