Sulisobenzone

Synonyms

5-Benzoyl-4-hydroxy-2-methoxybenzene sulfonic acid; 5-Benzoyl-4-hydroxy-2-methoxybenzolsulfonsaeure; Benzenesulfonic acid, 5-benzoyl-4-hydroxy-2-methoxy-; Uvinul MS-40 substanz; 1-Phenol-4-sulfonic acid, 2-benzoyl-5-methoxy- (6CI); 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid; 5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid; Benzophenone 4; MS 40; Seesorb 101S; Spectra-Sorb UV 284; Sulisobenzona [INN-Spanish]; Sulisobenzonum [INN-Latin]; Sungard; Syntase 230; Uval; Uvinuc MS 40; Uvinul; Uvinul MS 40; [ChemIDplus]

Category

Sunscreens

Description

Light tan solid; [Merck Index]

Sources/Uses

Used as ultraviolet absorber for leather and textiles, and ultraviolet screen for humans; Also used in cosmetics and shampoos; [Merck Index]

Comments

Caused 3% positive photo-patch tests in a series of Mayo Clinic patients; It is infrequently found to be a contact and photo-contact allergen; Cross reaction with oxybenzone and benzophenone may occur; [Marks, p. 222] No evidence of sensitization in man at 5%; [European Commission] Oral LD50 (rat) = 3530 mg/kg; [ChemIDplus] An irritant; [MSDSonline] See "Oxybenzone."

Biomedical References

1.3E-11 mm Hg

Yes

PACD (photoallergic contact dermatitis)

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Contact dermatitis, photoallergic

Processes

Industrial Processes with risk of exposure:

• Leather Tanning and Processing
• Textiles (Printing, Dyeing, or Finishing)