Tartrazine

Synonyms

4,5-Dihydro-5-oxo-1-(4-sulfophenyl)-4-((4-sulfophenyl)azo)-1H-pyrazole-3-carboxylic acid, trisodium salt; 1-(4-Sulfophenyl)-4-((4-sulfophenyl)azo)-1H-pyrazole-3-carboxylic; 1310 Yellow; 1409 Yellow; 1H-Pyrazole-3-carboxylic acid, 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-((4-sulfophenyl)azo)-, trisodium salt; 3-Carboxy-5-hydroxy-1-p-sulfophenyl-4-p-sulfophenylazopyrazole trisodium salt; A.F. Yellow No. 4; Acid Leather Yellow T; Acid Yellow 23; Acid Yellow T; Acilan Yellow GG; Airedale Yellow T; Aizen Tartrazine; Amacid Yellow T; Atul Tartrazine; Bucacid Tartrazine; C.I. 19140; C.I. 640; C.I. Acid Yellow 23; C.I. Acid Yellow 23, trisodium salt; C.I. Food Yellow 4; Calcocid Yellow MCG; Calcocid Yellow XX; Canacert Tartrazine; Certicol Tartrazol Yellow S; Cilefa Yellow T; Curon Fast Yellow 5G; D and C Yellow No. 5; D&C Yellow 5; Dolkwal Tartrazine; Dye FD and C Yellow No. 5; Dye Yellow Lake; E 102; Edicol Supra Tartrazine N; Egg Yellow A; Erio Tartrazine; Eurocert Tartrazine; FD & C Yellow No. 5; FD & C Yellow No. 5 Tartrazine; FD and C Yellow 5; FD&C Yellow No. 5; FD&G Yellow No. 5; Fenazo Yellow T; Food Yellow 4; Food Yellow 5; Food Yellow No. 4; Food Yellow No. 5; HD Tartrazine Supra; HD Tartrazine; Hexacert Yellow No. 5; Hexacol Tartrazine; Hidazid Tartrazine; Hispacid Fast Yellow T; Hydrazine Yellow; Hydroxine Yellow L; Kako Tartrazine; Kayaku Food Colour Yellow No. 4; Kayaku Tartrazine; KCA Foodcol Tartrazine PF; KCA Tartrazine PF; Kiton Yellow T; L Yellow Z 1020; L-Gelb 2 [German]; Lake Yellow; Lemon Yellow A; Lemon Yellow A Geigy; Maple Tartrazol Yellow; Mitsui Tartrazine; Naphtocard Yellow O; Neklacid Yellow T; Oxanal Yellow T; San-ei Tartrazine; Schultz No. 737; Sugai Tartrazine; Tartar Yellow FS; Tartar Yellow N; Tartar Yellow PF; Tartar Yellow S; Tartran Yellow; Tartraphenine; Tartrazine A Export; Tartrazine A Expo T; Tartrazine B; Tartrazine B.P.C.; Tartrazine C; Tartrazine C Extra; Tartrazine Extra Pure A; Tartrazine FD & C Yellow #5; Tartrazine FD&C Yellow #5; Tartrazine FQ; Tartrazine G; Tartrazine Lake; Tartrazine Lake Yellow N; Tartrazine M; Tartrazine MCGL; Tartrazine N; Tartrazine NS; Tartrazine O; Tartrazine O Specially Pure; Tartrazine T; Tartrazine XX; Tartrazine XX Specially Pure; Tartrazine XXX; Tartrazine Yellow; Tartrazine Yellow 5; Tartrazol BPC; Tartrazol Yellow; Tartrine Yellow O; Trisodium 3-carboxy-5-hydroxy-1-p-sulfophenyl-4-p-sulfophenylazopyrazole; Trisodium 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-((4-sulfophenyl)azo)-1H-pyrazole-3-carboxylate; Unitertracid Yellow TE; Usacert Yellow No. 5; Vondacid Tartrazine; Wool Yellow; Xylene Fast Yellow GT; Y-4; Yellow Lake 69; Yellow No. 5; Yellow No. 5 FDC; Zlut kysela 23 [Czech]; Zlut pigment 100 [Czech]; Zlut potravinarska 4 [Czech]; m-8847; [ChemIDplus]

Category

Azo Dyes

Description

Bright orange-yellow solid; [Merck Index] Hygroscopic; [HSDB] Orange powder; [MSDSonline]

Sources/Uses

Used as dye for wool, silk, food, drugs, cosmetics, and pesticides; Used in biochemistry (indicator) and in sanitizing solutions for food-processing equipment, utensils, and other items that contact food; [HSDB]

Comments

An allergen; [Hawley] Its use in coloring oral medications has caused allergic reactions in small percentage of patients; In one study of 2210 patients exposed to tartrazine in drugs, 3.8% had allergic reactions that subsided within 48 hours; There were no allergies to drugs not containing tartrazine; No significant adverse effects were observed in rats during long term feeding studies; Intraperitoneal LD50 (rat) >2000 mg/kg; [HSDB] An irritant; May cause skin and respiratory sensitization after prolonged contact; [MSDSonline]

Reference Link #1

Biomedical References

Yes

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational
• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)
• Textiles (Printing, Dyeing, or Finishing)
• Using Disinfectants or Biocides