Terephthalic acid

Agent Name
Terephthalic acid
Alternative Name
p-Phthalic acid
CAS Number
100-21-0
Formula
C8-H6-O4
Major Category
Other Classes
Terephthalic acid formula graphical representation
Synonyms
1,4-Benzenedicarboxylic acid; Acide terephtalique [French]; Kyselina tereftalova [Czech]; TA 12; TA-33MP; Tephthol; WR 16262; p-Benzenedicarboxylic acid; p-Carboxybenzoic acid; p-Dicarboxybenzene; p-Phthalic acid; para-Phthalic acid; [ChemIDplus]
Category
Organic Acids
Description
White solid; [Hawley] Odorless or a slight acetic acid odor; [CHEMINFO] Off-white powder; [MSDSonline]
Sources/Uses
Used in wool processing and making plastic films and sheets; Also added to poultry feeds and to certain antibiotics to increase their effectiveness; [HSDB]
Comments
Practically nontoxic in acute, high-dose animal studies; In high-dose feeding studies in rats, it causes bladder stones and subsequent bladder cancers; The bladder cancers are thought to be secondary to the presence of bladder stones. [ACGIH] A skin and eye irritant; [ICSC] An irritant; Effects in high-dose animal studies include abnormal liver function tests; [MSDSonline]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
10 mg/m3
MAK
5 mg/m3, inhalable fraction
Vapor Pressure
9.2E-06 mm Hg
Explanatory Notes
Flash point = 260 deg C; [ICSC]
NFPA
must be preheated

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: