Agent Name
Terephthalic acid
Alternative Name
p-Phthalic acid
Major Category
Other Classes
Synonyms
1,4-Benzenedicarboxylic acid; Acide terephtalique [French]; Kyselina tereftalova [Czech]; TA 12; TA-33MP; Tephthol; WR 16262; p-Benzenedicarboxylic acid; p-Carboxybenzoic acid; p-Dicarboxybenzene; p-Phthalic acid; para-Phthalic acid; [ChemIDplus]
Description
White solid; [Hawley] Odorless or a slight acetic acid odor; [CHEMINFO] Off-white powder; [MSDSonline]
Sources/Uses
Used in wool processing and making plastic films and sheets; Also added to poultry feeds and to certain antibiotics to increase their effectiveness; [HSDB]
Comments
Practically nontoxic in acute, high-dose animal studies; In high-dose feeding studies in rats, it causes bladder stones and subsequent bladder cancers; The bladder cancers are thought to be secondary to the presence of bladder stones. [ACGIH] A skin and eye irritant; [ICSC] An irritant; Effects in high-dose animal studies include abnormal liver function tests; [MSDSonline]
Skin Designation (ACGIH)
Insufficient data
MAK
5 mg/m3, inhalable fraction
Vapor Pressure
9.2E-06 mm Hg
Explanatory Notes
Flash point = 260 deg C; [ICSC]
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Processes
Industrial Processes with risk of exposure: