Major Category
Pesticides
Synonyms
(3-((6-Chloro-3-pyridinyl)methyl)-2-thiazolidinylidene)cyanamide; Calypso; Calypso 70WG; Cyanamide, (3-((6-chloro-3-pyridinyl)methyl)-2-thiazolidinylidene)-; [ChemIDplus]
Category
Insecticides, Neonicotinoid
Description
Odorless solid; [HSDB]
Sources/Uses
Used as insecticide to protect cotton, pome fruit, vegetables, and potatoes; [HSDB] A chloronicotinoid insecticide that inhibits nicotinic acetylcholine receptors; Registered for outdoor use on cotton and pome fruits; [Reference #1]
Comments
TLV Basis: Liver injury; effects on thyroid and central nervous system; cancer of thymus and uterus in animals; "Cancer outcomes from long-term feeding studies in rodents resulted in increased incidence of thyroid, uterine and ovarian tumors, with a NOAEL of 2.5 mg/kg body weight per day." One death from intentional ingestion of undiluted liquid--100 ml (21.7%); Patient had seizures within 2 hours and cardiac arrest within 36 hours. [ACGIH]
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.2 mg/m3, inhalable particulate matter
Vapor Pressure
6E-12 mm Hg
Lethal Concentration
LC50 (rat) = 1,223 mg/m3/4h
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
ACGIH Carcinogen
Confirmed Animal
Processes
Industrial Processes with risk of exposure: