Thiodiglycol
Agent Name
Thiodiglycol
CAS Number
111-48-8
Formula
C4-H10-O2-S
Major Category
Other Classes
Synonyms
2,2'-Thiobisethanol; 2,2'-Thiodiethanol; 2,2'-Thiodiglycol; Bis(2-hydroxyethyl) sulfide; Bis(2-hydroxyethyl) thioether; Bis(2-hydroxyethyl)sulfide; Bis(beta-hydroxyethyl) sulfide; Bis(beta-hydroxyethyl)sulfide; Di(2-hydroxyethyl) sulfide; Glyecine A; Kromfax solvent; Sulfide, bis(2-hydroxyethyl); Tedegyl; Thiodiethanol; Thiodiethylene glycol; Thiodiglycolum [INN-Latin]; Tiodiglicol [INN-Spanish]; Tiodiglicolo; Tiodiglicolo [DCIT]; beta,beta'-Dihydroxydiethyl sulfide; beta,beta'-Dihydroxyethyl sulfide; beta-Hydroxyethyl sulfide; Ethanol, 2,2'-thiobis-; Ethanol, 2,2'-thiodi-; [ChemIDplus]
Category
Sulfur Compounds (Alcohols)
Description
Colorless viscous liquid; [ICSC] Colorless to yellowish liquid with an unpleasant odor; [Reference #1] Colorless or pale yellow liquid with a stench; [Alfa Aesar MSDS]
Sources/Uses
A hydrolysis product of sulfur mustard (chemical weapon); Used as an intermediate for elastomers and antioxidants, a solvent for dyes in textile printing, to make ink for ball-point pens, and a precursor to mustard gas; Also used in the paint, lacquer, and varnish industry; in the polymers industry; and as a fixing agent, process regulator, and stabilizer;
[HSDB] Used to make pulp, paper products, furniture, paints, pigments, dyestuffs, varnishes, coatings, and inks; Also used as a solvent for coloring paper, a softener for special rubbers, and possibly as an antioxidant in cosmetics; [OECD SIDS: Thiodiglycol - 2004]
Comments
A mild eye and respiratory tract irritant; [ICSC] Causes mild skin irritation and moderate eye irritation in experimental animals; Not sensitizing in guinea pig maximization test; No evidence of mutagenicity; Emergency treatment: "Glycols"; [HSDB] An eye irritant; [eChemPortal: ESIS] A mild skin and moderate eye irritant; Causes diffuse hepatitis and other GI and endocrine changes in subcutaneous lethal-dose study of mice; [RTECS] An eye irritant; [Alfa Aesar MSDS]
Restricted
Manufacture and export strictly controlled under the International Chemical Weapons Convention (can be used to make sulfur mustard); [OECD SIDS: Thiodiglycol - 2004]
Biomedical References
Exposure Assessment
Vapor Pressure
0.00323 mm Hg
Explanatory Notes
VP from ChemIDplus;
NFPA
must be preheated
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: