Thiofanox

Synonyms

1-(2,2-Dimethyl-1-methylthiomethylpropylideneamino-oxy)-N-methylformamide; 2-Butanone, 3,3-dimethyl-1-(methylthio)-, O-((methylamino)carbonyl)oxime (9CI); 3,3-Dimethyl-1-(methylthio)-2-butanone O-((methylamino)carbonyl)oxime; 3,3-Dimethyl-1-(methylthio)-2-butanone-O-((methylamino)carbonyl)oxime; 3,3-Dimethyl-1-methylthiobutanone O-methylcarbamoyloxime; Benelux; DS-15647; Dacamox; Diamond Shamrock DS-15647; Thiofanocarb; Thiophanox; [ChemIDplus] UN2757

Category

Carbamate Insecticides

Description

Colorless solid with a pungent odor; [HSDB] Colorless crystalline solid with an acrid odor; [MSDSonline]

Sources/Uses

Used as insecticide, acaricide, and nematocide; Used to protect sugar beets and potatoes in the EU; [HSDB]

Comments

NOEL in 90 day feeding studies with dogs and rats was 1 mg/kg/day; Symptoms of cholinesterase inhibition lasted 3-4 hours in rats at 4 mg/kg/day; [HSDB] A cholinesterase inhibitor; [CAMEO] See "CARBAMATE INSECTICIDES."

Not registered as a pesticide for use in the US; [HSDB]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

0.00017 mm Hg

LC50 (rat) = 70 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Carbamate pesticide, solid, toxic."

Other Poison

Carbamate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)