Thiometon

Synonyms

2-Ethylthioethyl O,O-dimethyl phosphorodithioate; BAY 23129; Bay 21/116; Bayer 23129; Compound M-81; Dithiometasystox; Dithiomethon; Dithiometon [French]; Dithiophosphate de O,O-dimethyle et de S-(2-ethylthio-ethyle) [French]; Ebicid; Ekatim; Ekatin; Ekatin ULV; Ekatin WF; Ekatin WF ULV; Ekatin aerosol; Ekatine-25; Ethanethiol, 2-(ethylthio)-, S-ester with O,O-dimethyl phosphorodithioate; Intrathion; Intration; Luxistelm; M 81; M 81 (van); O,O-Dimethyl S-(2-(ethylthio)ethyl) phosphorodithioate; O,O-Dimethyl-S-(2-aethylthio-aethyl)-dithio phosphat [German]; O,O-Dimethyl-S-(2-ethylmercaptoethyl) dithiophosphate; O,O-Dimethyl-S-(2-ethylthio-ethyl)-dithiofosfaat [Dutch]; O,O-Dimethyl-S-2-ethylmerkaptoethylester kyseliny dithiofosforecne [Czech]; O,O-Dimetil-S-(etiltio-etil)-ditiofosfato; O,O-Dimetil-S-(etiltio-etil)-ditiofosfato [Italian]; Phosphorodithioic acid, O,O-dimethyl S-(2-ethylthio)ethyl ester; Phosphorodithioic acid, S-(2-(ethylthio)ethyl) O,O-dimethyl ester; S-(2-(Ethylthio)ethyl) O,O-dimethyl phosphorodithioate (8CI)(9CI); S-(2-(Ethylthio)ethyl) O,O-dimethyl phospohorodithioate; S-(2-(Ethylthio)ethyl) O,O-dimethylphosphorodithionate; S-(2-(Ethylthio)ethyl)dimethyl phosphorothiolothionate; SAN 230; Thiometon; Veltin; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Colorless oily liquid; [ICSC]

Sources/Uses

Used as systemic insecticide to protect ornamentals, fruits, vegetables, and other crops; [HSDB]

Comments

A cholinesterase inhibitor that may cause nervous system effects; Can be absorbed through skin; [ICSC] A weak mutagen; [HSDB] Cholinesterase inhibition observed in short term animal studies, but no adverse histopathological or other changes; No evidence of delayed neurotoxicity, significant reproductive toxicity, or teratogenicity in animal studies; [INCHEM PDS: Thiometon - 1988] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

1.7E-05 mm Hg

LCLo (rat) = 20 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)