Thionazin

Synonyms

AC 18133; ACC 18133; American Cyanamid 18133; CL 18133; Cynem; Cynophos; Diethyl O-2-pyrazinyl phosphorothionate; EN 18133; ENT 25,580; Ethyl pyrazinyl phosphorothioate; Experimental nematocide 18,133; Nemafos; Nemafos 10 G; Nemaphos; Nematocide GR; O,O-Diaethyl-O-(2-pyrazinyl)-thionophosphat [German]; O,O-Diaethyl-O-(pyrazin-2-yl)-monothiophosphat [German]; O,O-Diethyl O,2-pyrazinyl phosphorothioate; O,O-Diethyl O-2-pyrazinyl phosphorothionate; O,O-Diethyl O-pyrazinyl phosphorothioate; O,O-Diethyl O-pyrazinyl thiophosphate; Phosphorothioic acid, O,O-diethyl O-2-pyrazinyl ester; Phosphorothioic acid, O,O-diethyl O-pyrazinyl ester; Pyrazinol, O-ester with O,O-diethyl phosphorothioate; Thionazin [BSI]; Thionazine; Zinofos; Zinophos; Zinophos 10-G granular; Zinophos 4-E emulsifiable concentrate; Zinphos Insecticide, Nematicide; Zynophos; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Nearly colorless liquid when pure; Technical product: Light brown to tan liquid; [HSDB] Clear very deep brown liquid; [MSDSonline]

Sources/Uses

Used as soil insecticide and nematocide to protect vegetables, corn, and other crops; No longer commercially produced in the US; [HSDB] Used in insecticides, fungicides, and nematocides; [CAMEO]

Comments

A cholinesterase inhibitor; [CAMEO] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Not registered with the EPA for use as pesticide in the US; [CAMEO]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

0.003 mm Hg

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)