Triazophos

Synonyms

1-Phenyl-1,2,4-triazolyl-3-(O,O-diethylthionophosphate); 1-Phenyl-3-(O,O-diethyl-thionophosphoryl)-1,2,4-triazole; HOE 2960; HOE 2960 OJ; Hostathion; O,O-Diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) phosphorothioate (8CI)(9CI); O,O-Diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl)phosphorothioate; Phosphorothioic acid, 0,0-diethyl 0-(1-phenyl-1H-1,2,4-triazol-3-yl) ester; Triazofosz (Hungarian); Triazofos; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Light brown liquid; mp = 0-5 deg C; [Merck Index] Yellowish liquid; [HSDB]

Sources/Uses

Used as broad spectrum insecticide and acaricide for fruit and cereals; [HSDB]

Comments

A cholinesterase inhibitor; Can be absorbed through skin; [CAMEO] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Not registered with the EPA for use as pesticide in the US; [CAMEO] Banned in the EU for use as a biocide and agricultural insecticide; [eChemPortal: ESIS]

Reference Link #1

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

2.9E-06 mm Hg

LC50 (rat) = 450 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)