Triethylene glycol monobutyl ether

Synonyms

2-(2-(2-Butoxyethoxy)ethoxy)ethanol; 3,6,9-Trioxa-1-tridecanol; Butoxytriethylene glycol; Butoxytriglycol; Dowanol TBAT; Poly-Solv TB; Triethylene glycol butyl ether; Triethylene glycol mono-n-butyl ether; Triethylene glycol n-butyl ether; Triglycol monobutyl ether; Ethanol, 2-(2-(2-butoxyethoxy)ethoxy)-; [ChemIDplus] TGBE; [eChemPortal: SIDSUNEP]

Category

Glycol Ethers (E Series)

Description

Colorless liquid; [ICSC] Colorless to yellow hygroscopic liquid; [CHEMINFO] Faintly yellow-green liquid; [MSDSonline]

Sources/Uses

Used as plasticizer, intermediate, and solvent (resins, paints, metal cleansing agents, pharmaceuticals, cosmetics, greases, and oils) ; Also used in wood preservatives, cutting and hydraulic oils, inks, and in the leather, textile, and transportation industries; [HSDB] Used mainly in automotive hydraulic brake fluids; Also used as a solvent and intermediate; [eChemPortal: SIDSUNEP]

Comments

High-dose animal studies: Not genotoxic; Doses >1000 mg/kg/day cause liver injury; Repeated oral doses >4000 mg/kg/day cause testicular injury; Not a developmental toxin at doses <1000 mg/kg/day; No deaths after inhalation of saturated solution for 8 hours; [OECD SIDS: High Boiling Ethylene Glycol Ethers - 2002] An eye and mild skin irritant; [ICSC] In lethal-dose animal studies after oral administration, causes flaccid paralysis; [RTECS] A strong eye irritant, based on animal studies; [HSDB] A mild to moderate skin irritant; Very irritating to eyes; [eChemPortal: SIDSUNEP] May cause serious eye injury; [eChemPortal: ESIS] See "GLYCOL ETHERS."

Biomedical References

0.0025 mm Hg

Explanatory Notes

VP from ChemIDplus;

must be preheated

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Applying Wood Preservatives
• Leather Tanning and Processing
• Metal Degreasing
• Metal Machining
• Painting (Solvents)
• Textiles (Fiber & Fabric Manufacturing)