Triethylene glycol monoethyl ether

Synonyms

2-(2-(2-Ethoxyethoxy)ethoxy)ethanol; 3,6,9-Trioxaundecan-1-ol; Dowanol TE; Ethoxytriethylene glycol; Ethoxytriglycol; Ethyltriglycol; Poly-Solv TE; Triethylene glycol ethyl ether; Triglycol monoethyl ether; Ethanol, 2-(2-(2-ethoxyethoxy)ethoxy)-; [ChemIDplus] TGEE; [eChemPortal: SIDSUNEP]

Category

Glycol Ethers (E Series)

Description

Colorless hygroscopic liquid; [ICSC] Odorless; [HSDB]

Sources/Uses

Used as raw material for hydraulic brake fluids; Also used in coatings, printing inks, specialty chemicals, cleaning products, cutting oils, deicing agents, anti-sudsing agent for finely powdered materials, and food contact plastics (plasticizer); [HSDB] 95% used to make hydraulic brake fluid; [OECD SIDS: 2-(2-(2-Ethoxyethoxy)ethoxy)ethanol - 1996]

Comments

In lethal-dose studies, causes congestion of kidneys and liver; One of 5 male rats exhibited testicular effects that were thought to be unrelated to treatment; No developmental toxicity in rats receiving 1000 mg/kg/day; Not expected to be genotoxic; [OECD SIDS: 2-(2-(2-Ethoxyethoxy)ethoxy)ethanol - 1996] Defats the skin; [ICSC] A skin and mild eye irritant, based on animal studies; [eChemPortal: SIDSUNEP] May cause irritation; [MSDSonline] See "GLYCOL ETHERS."

Biomedical References

0.00224 mm Hg

LC50 (rat) > 50,000 mg/m3/4h

Explanatory Notes

VP from ChemIDplus;

must be preheated

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Metal Machining
• Painting (Solvents)