Trimethylthiourea
Agent Name
Trimethylthiourea
CAS Number
2489-77-2
Formula
C4-H10-N2-S
Major Category
Nitrogen Compounds
Synonyms
1,1,3-Trimethyl-2-thiourea; 1,1,3-Trimethylthiourea; 1,3,3-Trimethylthiourea; N,N,N'-Trimethylthiourea; Thiate E; Thiourea, trimethyl-; Urea, 1,1,3-trimethyl-2-thio-; Thiourea, N,N,N'-trimethyl-; Trimethyl-2-thiourea; [ChemIDplus]
Category
Thiourea Compounds
Description
Solid; [HSDB] Off-white crystals; [Maybridge MSDS]
Sources/Uses
Used as a curing agent for chloroprene/neoprene rubbers and epichlorohydrin elastomers; [HSDB]
Comments
No evidence of carcinogenicity in mice or male rats, but follicular cell carcinomas of the thyroid were observed in female rats in a 77 week feeding study; [NTP] Causes thyroid hypofunction and changes in thyroid weight in seven day continuous oral study of mice at 210 mg/kg; [RTECS] An irritant; [Maybridge MSDS]
Reference Link #1
Biomedical References
Exposure Assessment
Vapor Pressure
3 mm Hg
Explanatory Notes
VP from ChemIDplus;
Adverse Effects
Skin Sensitizer
Yes
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: