Triphenyl phosphite

Agent Name
Triphenyl phosphite
CAS Number
Major Category
Other Classes
Triphenyl phosphite formula graphical representation
ADK Stab TPP; Advance TPP; EFED; JP 360; Mellite 310; P 36; P 36 (stabilizer); Phenyl phosphite; Phosclere T 36; Phosphorous acid, triphenyl ester; Stabilizer P 36; Sumilizer TPP-R; Sumilizer TTP-R; TP 1 (plasticizer); TPP; TPP (VAN); TPP (plasticizer); Trifenoxyfosfin [Czech]; Trifenylfosfit [Czech]; Triphenoxyphosphine; Tris(phenoxy)phosphine; Weston TPP; [ChemIDplus]
Phosphite Compounds
Colorless to pale yellow solid or oily liquid; mp = 22-25 deg C; [ICSC] Pleasant odor; [HSDB] Off-white or yellow low melting solid; mp = 22-24 deg C; [MSDSonline]
Used as a stabilizer/antioxidant (rubber and plastics industries), metal scavenger, epoxy resin diluent, and insecticide synergist; [HSDB] Used as a reducing agent and in paints, lacquers, and varnishes; [IUCLID]
Reacts with water; A skin, eye, and respiratory tract irritant; May cause skin sensitization; High concentrations may cause nervous system effects; [ICSC] An eye and severe skin irritant; A mild sensitizer; Emergency treatment: "TOCP and related agents"; Following exposure to >6-7 mg/kg of TOCP, patients have acute GI symptoms of vomiting, diarrhea and abdominal pain; After a delay of 8-35 days, patients develop peripheral neuropathy (flaccid paralysis) that resolves over the next 2-3 months in some patients; Some patients remain permanently paralyzed; [HSDB] Causes flaccid paralysis in rats after subcutaneous doses >2000 mg/kg; [RTECS] A skin irritant; [CAMEO] A skin and eye irritant; [eChemPortal: ESIS] An irritant; Harmful if swallowed; Toxic to aquatic organisms; [MSDSonline] See "Triorthocresyl phosphate."
Biomedical References

Exposure Assessment

Lethal Concentration
LC (rat) > 6,700 mg/m3/4h
must be preheated

Adverse Effects

Other CNS neurotoxin

Diseases, Processes, and Activities Linked to This Agent