Tris(1,3-dichloro-2-propyl)phosphate

Synonyms

1,3-Dichloro-2-propanol phosphate (3:1); 2-Propanol, 1,3-dichloro-, phosphate (3:1); CRP; CRP (fireproofing agent); Emulsion 212; Fosforan troj-(1,3-dwuchloroizopropylowy) [Polish]; Fyrol FR 2; PF 38; PF 38/3; Phosphoric acid, tris(1,3-dichloro-2-propyl) ester; TDCPP; Tri(beta,beta'-dichloroisopropyl)phosphate; Tris(1,3-dichloro-2-propyl) phosphate; Tris(1,3-dichloroisopropyl)phosphate; Tris(1-chloromethyl-2-chloroethyl)phosphate; Tris(2-chloro-1-(chloromethyl)ethyl)phosphate; [ChemIDplus]

Category

Organophosphates, Other

Description

mp = 27 deg C; [ChemIDplus] Clear colorless liquid; [CAMEO]

Sources/Uses

Used as a flame retardant (plastics, flexible urethane foams, and textile backcoatings) and plasticizer; [HSDB]

Comments

Oral LD50 (mouse) = 2250 mg/kg; (Effects included tremor and seizures.) May cause skin and eye irritation; A study of a factory workers did not find any significantly increased morbidity in exposed versus unexposed workers; [HSDB] Usually found as super-cooled liquid at room temperature; May cause skin and respiratory tract irritation; A cholinesterase inhibitor; [CAMEO] A skin and eye irritant, based on animal studies; [eChemPortal: NICNAS] A skin irritant; Effects in high-dose animal studies include convulsions; [MSDSonline]

Biomedical References

7.36E-08 mm Hg

LC50 (rat) > 5,220 mg/m3/4h

Explanatory Notes

VP = 10.3 mm Hg at 25 deg C; [CAMEO] VP = 0.0098 mm Hg at 30 deg C; [eChemPortal: NICNAS] VP = 0.01 mm Hg at 30 deg C; [eChemPortal: HPVIS] VP from ChemIDplus;

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning