Tris(2,3-dibromopropyl) phosphate

Agent Name
Tris(2,3-dibromopropyl) phosphate
CAS Number
126-72-7
Formula
C9-H15-Br6-O4-P
Major Category
Other Classes
Tris(2,3-dibromopropyl) phosphate formula graphical representation
Synonyms
(2,3-Dibromopropyl) phosphate; 1-Propanol, 2,3-dibromo-, phosphate (3:1); 2,3-Dibromo-1-propanol phosphate; 2,3-Dibromo-1-propanol phosphate (3:1); 3PBR; APEX 462-5; Anfram 3PB; Bromkal P 67-6HP; ES685; FireMaster T 23; Firemaster LV-T 23P; Firemaster T23P; Firemaster T23P-LV; Flacavon R; Flamex T 23P; Flammex AP; Flammex LV-T 23P; Flammex T 23P; Fyrol HB32; Phoscon PE 60; Phoscon UF-S; Phosphoric acid, tris(2,3-dibromopropyl) ester; T 23P; TDBP [Czech]; TDBPP; TRIS; Tris (VAN); Tris (flame retardant); Tris(2,3-dibromo-1-propyl) phosphate; Tris(2,3-dibromopropyl) phosphoric acid ester; Tris(2,3-dibromopropyl)phosphate; Tris(dibromopropyl)phosphate; Tris-(2,3-dibrompropyl)fosfat [Czech]; Tris-2,3-dibrompropyl ester kyseliny fosforecne [Czech]; Tris-BP; Zetifex ZN; Zetofex ZN; [ChemIDplus]
Category
Organophosphates, Other
Description
Colorless liquid; mp = 5.5 deg C; [ICSC] Nearly colorless to pale yellow liquid; [HSDB]
Sources/Uses
Used as flame retardant (rigid foams, clear cast acrylic sheet, lacquers, styrene-butadiene rubber, latex rubber, cured unsaturated polyesters, and plastics); From 1972-1976, infants and children were exposed by skin absorption and ingestion to TRIS treated garments; [HSDB]
Comments
Probably carcinogenic to humans; [ICSC] Causes eye and severe skin irritation; Oral LD50 (rat) = 1010 mg/kg; Percutaneous LD50 (rabbit) >8000 mg/kg; [HSDB] An eye and strong skin irritant; May cause skin sensitization; May cause liver and kidney injury; Can be absorbed through skin; [CAMEO] Effects in acute, high-dose animal studies include kidney and liver damage; Has a low skin sensitization potential; [Reference #1] A skin irritant; [MSDSonline]
Restricted
Banned for use in the US in 1977; [HSDB]
Biomedical References

Exposure Assessment

Vapor Pressure
0.00019 mm Hg

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Probable (2a)
NTP Carcinogen
Anticipated human carcinogen

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: