Cyclohexanol

Agent Name
Cyclohexanol
CAS Number
108-93-0
Formula
C6-H12-O
Major Category
Other Classes
Cyclohexanol formula graphical representation
Synonyms
1-Cyclohexanol; Adronal; Adronol; Anol; Cicloesanolo [Italian]; Cyclohexanol; Cyclohexanone cyclohexanol mixture; Cyclohexyl alcohol; Cykloheksanol [Polish]; Hexahydrophenol; Hexalin; Hydralin; Hydrophenol; Hydroxycyclohexane; Naxol; Phenol, hexahydro-; [ChemIDplus] UN1993
Category
Alcohols and Polyols, Other
Description
Sticky solid or colorless to light-yellow liquid (above 77 degrees F) with a camphor-like odor; [NIOSH]
Sources/Uses
Used in the production of nylon, paints, plastics, detergents, textiles, and pesticides; [ACGIH]
Comments
Liquid or solid form causes first degree burns on short exposure; [CHRIS] Skin absorption and narcosis seen in acute animal studies; [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] Causes liver and kidney injury in high-dose animal studies; [HSDB]
Biomedical References

Exposure Assessment

BEI
Screen for 1,2-Cyclohexandiol (with hydrolysis) in urine at end of shift at end of workweek;Screen for Cyclohexanol (with hydrolysis) in urine at end of shift;
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
50 ppm
PEL (OSHA)
50 ppm
IDLH (NIOSH)
400 ppm
Excerpts from Documentation for IDLHs
Human data: The estimated acceptable concentration for 8 hours was reported in volunteers to be less than 100 ppm [Nelson et al. 1943].
Vapor Pressure
0.657 mm Hg
Odor Threshold Low
0.05 ppm
Odor Threshold High
0.15 ppm
Lethal Concentration
LC (rat) > 6,500 mg/m3/1h (inhalation)
Explanatory Notes
Detection odor threshold from AIHA (mean = 0.16 ppm); Flash point = 63 deg C; VP from HSDB;
Half Life
No reports found; [TDR, p. 430]
Reference Link #2
NFPA
high ambient temp required

Adverse Effects

Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Dermatotoxin
Skin burns

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: