2-Nitrophenol
Agent Name
2-Nitrophenol
CAS Number
88-75-5
Formula
C6-H5-N-O3
Major Category
Nitrogen Compounds
Synonyms
2-Hydroxynitrobenzene; 2-Nitrophenol; Phenol, 2-nitro-; Phenol, o-nitro-; o-Hydroxynitrobenzene; o-Nitrofenol [Czech]; o-Nitrophenol; [ChemIDplus] UN1663
Category
Nitrophenols
Description
Light yellow solid with a peculiar aromatic smell;
Sources/Uses
Used to produce drugs, fungicides, and dyes; used to darken leather; [ATSDR ToxProfiles]
Comments
4-Nitrophenol is more toxic than 2-nitrophenol in animals. Rats exposed to 112 mg/m3 for 2 weeks develop methemoglobinemia. No effect after dust exposures of 30 mg/m3 for 3-6 hours/day, 5 days a week for 4 weeks; [ATSDR ToxProfiles] Can be absorbed through intact skin; [HSDB] A mild skin and eye irritant; Can induce methemoglobinemia after ingestion; [ICSC]
Biomedical References
Exposure Assessment
Vapor Pressure
0.113 mm Hg
Explanatory Notes
VP from HSDB;
Reference Link #2
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.