p-tert-Butylphenol

Synonyms

1-Hydroxy-4-tert-butylbenzene; 2-tert-Butylphenol; 4-(1,1-Dimethylethyl)phenol; 4-t-Butylphenol; 4-tert-Butylphenol; Butylphen; PTBP; Phenol, 4-(1,1-dimethylethyl)-; Phenol, p-(tert-butyl)-; Ucar butylphenol 4-T; Ucar butylphenol 4-T flake; p-terc.Butylfenol [Czech]; [ChemIDplus] UN2430

Category

Phenols

Description

White solid with a disinfectant-like odor; [CAMEO] Hygroscopic; [ICSC] White crystalline powder; [MSDSonline]

Sources/Uses

Used as a plasticizer and intermediate; [Hawley]

Comments

A severe skin, eye, and respiratory tract irritant; May cause skin sensitization and dermatitis after prolonged contact; May cause skin depigmentation; After chronic exposure, may cause effects on the liver and nervous system; [ICSC] Danger of cutaneous absorption; Danger of skin sensitization; [MAK] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; No sensitizing effects known; Inhalation may cause chemical pneumonitis; Can be absorbed through skin; [MSDSonline]

Biomedical References

0.08 ppm

0.0381 mm Hg

LCLo (rat) = 911.46 ppm/4h

Explanatory Notes

Flash Point = 235 deg F; [CAMEO] The Guide in the Emergency Response Guidebook is for "Alkyl phenols, liquid, n.o.s. (including C2 - C12 homologues)." VP from ChemIDplus;

Yes

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic