Dicyclohexylcarbodiimide
Agent Name
Dicyclohexylcarbodiimide
CAS Number
538-75-0
Formula
C13-H22-N2
Major Category
Nitrogen Compounds
Synonyms
1,3-Dicyclohexylcarbodiimide; Bis(cyclohexyl)carbodiimide; Carbodicyclohexylimide; DCC; DCCD; DCCI; N,N'-Dicyclohexylcarbodiimide; N,N'-Methanetetraylbiscyclohexaamine; Carbodiimide, dicyclohexyl-; Cyclohexaamine, N,N'-methanetetraylbis- (9CI); Cyclohexanamine, N,N'-methanetetraylbis-; [ChemIDplus]
Category
Other Nitrogen Compounds
Description
White solid with a sweet odor; [Hawley] White melt; mp = 33-36 deg C; [MSDSonline]
Sources/Uses
Used in chemical synthesis; [Hawley] Used as a coupling reagent in peptide chemistry; [Kanerva, p. 1781]
Comments
A skin, eye, and respiratory tract irritant; High concentrations can be corrosive and very damaging to tissue; [CAMEO] Contact allergen; [Merck Index] An irritant; May cause serious eye injury; May cause skin sensitization; Can be absorbed through skin; Effects in high-dose animal studies include convulsions; [MSDSonline] Danger of skin sensitization; [MAK]
Reference Link #1
Biomedical References
Exposure Assessment
Lethal Concentration
LC50 (rat) = 159 mg/m3/6h
Explanatory Notes
Flash Point > 235 deg F; [CAMEO]
Adverse Effects
Skin Sensitizer
Yes
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: