Isoeugenol and isomers

Agent Name
Isoeugenol and isomers
CAS Number
97-54-1, 5912-86-7, 5932-68-3
Formula
C10-H12-O2
Major Category
Other Uses
Synonyms
97-54-1: 1-(3-Methoxy-4-hydroxyphenyl)-1-propene; 1-Hydroxy-2-methoxy-4-propen-1-ylbenzene; 1-Hydroxy-2-methoxy-4-propenylbenzene; 2-Methoxy-4-(1-propenyl)phenol; 2-Methoxy-4-propenylphenol; 3-Methoxy-4-hydroxy-1-propen-1-ylbenzene; 4-Hydroxy-3-methoxy-1-propen-1-ylbenzene; 4-Hydroxy-3-methoxy-1-propenylbenzene; 4-Hydroxy-3-methoxypropenylbenzene; 4-Propenylguaiacol; Phenol, 2-methoxy-4-(1-propenyl)-; Phenol, 2-methoxy-4-propenyl-; [ChemIDplus] 5912-86-7: Isoeugenol cis-form; (Z)-Isoeugenol; cis-2-Methoxy-4-propenylphenol; cis-4-Propenylguaiacol; cis-Isoeugenol; (Z)-2-Methoxy-4-(prop-1-enyl)phenol; Phenol, 2-methoxy-4-propenyl-, (Z)-; [ChemIDplus] 5932-68-3: Isoeugenol trans-form; (E)-Isoeugenol; trans-2-Methoxy-4-propenylphenol; trans-Isoeugenol; trans-p-Propenylquaiacol; (E)-2-Methoxy-4-(prop-1-enyl)phenol; Phenol, 2-methoxy-4-(1-propenyl)-, (E)- (9CI); Phenol, 2-methoxy-4-propenyl-, (E)-; [ChemIDplus]
Category
Food Additives
Description
97-54-1: Pale yellow oily liquid with a spice-clove odor; [CAMEO] Clear light yellow-green viscous liquid; [MSDSonline] 5912-86-7: Liquid; [Merck Index] 5932-68-3: Solid; [Merck Index]
Sources/Uses
Occurs in ylang-ylang oil and other essential oils; [CAMEO] Used in perfumes, vanillin, and flavoring agents; [Hawley] Approved by the FDA as a food flavor; Used in cosmetics, medications, and dental materials; Occurs naturally in the oils of clove, ylang-ylang, tuberose, and jonquil; [Marks, p. 175]
Comments
An irritant; Possible sensitizer; [MSDSonline] Isoeugenol is a fragrance allergen that causes allergic contact dermatitis. [Marks, p. 168, 172] Danger of skin sensitization; [MAK] Common allergen in cosmetics and perfumes; [Kanerva, p. 1805] See "Eugenol."
Biomedical References

Exposure Assessment

Vapor Pressure
0.02 mm Hg
Explanatory Notes
Flash Point = 235 deg F; [CAMEO]
NFPA
high ambient temp required

Adverse Effects

Skin Sensitizer
Yes
IARC Carcinogen
Possible (2b)

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: