Sodium chloroacetate
Agent Name
Sodium chloroacetate
CAS Number
3926-62-3
Formula
C2-H3-Cl-O2.Na
Major Category
Metals
Synonyms
Chloroacetic acid sodium salt; Chloroctan sodny [Czech]; Dow defoliant; Monoxone; SMA; SMCA; Sodium monochloracetate; Sodium monochloroacetate; Acetic acid, 2-chloro-, sodium salt (1:1); [ChemIDplus] UN2659
Category
Organic Acids, Metal Salts
Description
White, odorless, solid; [Hawley] White powder; [MSDSonline]
Sources/Uses
Used to make herbicides, dyes, and pharmaceuticals; A defoliant; [Hawley]
Comments
An eye and respiratory tract irritant; Toxic by ingestion or by inhalation after spraying; "The substance may cause effects on the central nervous system and cardiovascular system, resulting in convulsions, cardiac disorders and kidney impairment." [ICSC] Toxic to the liver in high-dose, animal-feeding studies; [AIHA] Highly toxic by inhalation, ingestion, and skin absorption; [CAMEO] An irritant; Effects in high-dose animal studies include convulsions and coma; [MSDSonline]
Biomedical References
Exposure Assessment
MAK
2 mg/m3, inhalable fraction
Vapor Pressure
0.865 mm Hg
WEEL
2.5 mg/m3
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: