Pyrogallol

Agent Name
Pyrogallol
CAS Number
87-66-1
Formula
C6-H6-O3
Major Category
Other Classes
Pyrogallol formula graphical representation
Synonyms
1,2,3-Benzenetriol; 1,2,3-Trihydroxybenzen [Czech]; 1,2,3-Trihydroxybenzene; 215; Benzene, 1,2,3-trihydroxy-; C.I. 76515; C.I. Oxidation Base 32; CI 76515; CI Oxidation Base 32; Fouramine Brown AP; Fourrine 85; Fourrine PG; PYROGALLOL; Pyro; Pyrogallic acid; [ChemIDplus]
Category
Phenols
Description
Odorless, white to gray solid; [CAMEO]
Sources/Uses
Used in photography and leather crafts; used in wool, fur, and hair dyeing; also used as an analytical chemistry reagent, an antioxidant for oils, and as a topical medication; [HSDB] Used in hair dyes and was used in photographic developers; [Kanerva, p. 1832] No longer used in hair dyes because of the frequency of allergic reactions; [Kanerva, p. 1516]
Comments
Reported human toxicity after ingestion includes methemoglobinemia, hemolysis of red blood cells, and damage to the liver and kidneys; [HSDB] An eye, respiratory tract, and mild skin irritant; May cause skin sensitization; [ICSC] Allergic contact dermatitis reported in hairdressers; [Kanerva, p. 1832] Toxic by ingestion with adverse effects including convulsions; [CAMEO]
Biomedical References

Exposure Assessment

Vapor Pressure
0.000479 mm Hg
Explanatory Notes
VP from HSDB;
Reference Link #2

Adverse Effects

Skin Sensitizer
Yes
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes