Isobutyl chloroformate
Agent Name
Isobutyl chloroformate
Alternative Name
Isobutyl chlorocarbonate
CAS Number
543-27-1
Formula
C5-H9-Cl-O2
Major Category
Toxic Gases & Vapors
Synonyms
Isobutyl chlorocarbonate; 2-Methylpropyl carbonochloridate; 2-Methylpropyl chloroformate; Chlorocarbonic acid isobutyl ester; Carbonochloridic acid, 2-methylpropyl ester; Formic acid, chloro-, isobutyl ester (8CI); [ChemIDplus] UN2742
Category
Acid Halides
Description
Clear liquid; [Merck Index] Colorless liquid with a pungent odor; [ICSC]
Sources/Uses
Used as A peptide reagent; [Hawley]
Comments
An eye and mucous membrane irritant (vapors); [Merck Index] Corrosive; [Hawley] Reacts with water evolving hydrogen chloride; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause pulmonary edema; [ICSC] Highly flammable; Reacts with water exothermically forming hydrogen chloride gas; Highly corrosive to skin, eyes, and mucous membranes; [CAMEO] Corrosive to skin and eyes; [eChemPortal: ERMA] A lachrymator; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline] See "CHLOROFORMATES."
Biomedical References
Exposure Assessment
TIH
Yes
MAK
0.2 ppm
Vapor Pressure
16.5 mm Hg
Adverse Effects
Lachrymator
Yes
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: