CHLORINATED NAPHTHALENES

Agent Name
CHLORINATED NAPHTHALENES
Alternative Name
CLASS
Major Category
Other Classes
Synonyms
CLASSES; Halowaxes
Category
Halowaxes
Description
Liquids, waxes, or high melting-point solids;
Sources/Uses
Have been used in cable insulation, wood preservation, engine oil additives, electroplating masking compounds, capacitors, refractive index testing oils, and dye production; Waste incineration is a source of environmental contamination; [Reference #1] Have been used as impregnants for condensers and capacitors, dipping-encapsulating compounds in electronic and automotive applications, temporary binders in the manufacture of ceramic components, in paper coatings, in precision casting of alloys, and as additives in gear oils and cutting compounds; [HSDB] Also used as supports for storage batteries, in textile dyeing, an oil additive, and a DDT solvent; See "2-Chloronaphthalene," "Halowax 1000," and "1-Choronaphthalene."
Comments
There are 75 possible congeners; Chlorinated naphthalenes bioaccumulate in fish; Bioaccumulation increases with degree of chlorination; Highly chlorinated naphthalenes, e.g., octachloronaphthalene, do not bioaccumulate because of poor absorption; Monitoring of seabird eggs between 1974 and 1987 showed decreasing levels of chlorinated naphthalenes; Target organs are liver (hepatitis) and skin (chloracne); LD50 values range from 3-1540 mg/kg body weight with the higher chlorinated congeners being more toxic; Chloracne and severe liver disease were reported in workers handling these chemicals in the 1930s and 1940s; Dermal application of Halowax 1014, containing penta- and hexachloronaphthalenes, caused chloracne in humans, but congeners with less chlorine did not cause chloracne after dermal application; [Reference #1]
Restricted
Not manufactured in the US since 1977; No longer used in capacitors or electric cable coverings; Largely discontinued as lubricants; No longer used as wood preservatives in the US; [HSDB]
Biomedical References

Exposure Assessment

Bioaccumulates
Yes
Half Life
1.5-2.4 years for hexa-isomers in human blood; [Reference #1]

Adverse Effects

Hepatotoxin
Occupational hepatotoxin (principal effect)
Dermatotoxin
Chloracne

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: