Imazaquin

Synonyms

2-(4,5-Dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl)-3-quinolinecarboxylic acid; 2-(4-Isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)quinoline-3-carboxylic acid; 2-(5-Isopropyl-5-methyl-4-oxo-2-imidazolin-2-yl)-3-quinolinecarboxylic acid; AC 252214; Imazaquine [ISO-French]; Scepter Herbicide; 3-Quinolinecarboxylic acid, 2-(4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl)-; [ChemIDplus]

Category

Herbicides, Imidazolinone

Description

Colorless or tan solid; Technical product: Odorless white solid; [HSDB] Yellowish grey solid; [EFSA]

Sources/Uses

Used as pre and post-emergence herbicide for soybeans, ornamentals, and turf; [Reference #1] Used in the EU in combination with chlormequat chloride (CAS# 999-81-5) as plant growth regulator for winter wheat and winter barley; [EFSA]

Comments

Weight loss, mild anemia, and skeletal muscle myopathy observed in chronic study of dogs; No developmental toxicity observed in rats or rabbits; No adverse effects in reproduction during multi-generational study of rats; No evidence of carcinogenicity, mutagenicity, or neurotoxicity; [Reference #1] Not irritating to rabbit skin or eyes; Not sensitizing to guinea pig skin; In 1-year feeding study of dogs at the highest tested dose (5,000 ppm), caused mild anemia, significantly elevated liver enzymes, and striated muscle myopathy with corresponding increase in blood CPK levels; Decreased body weight was the only treatment related effect in two year feeding studies of rats and mice; Increase in frequency and severity of pelvic calcification of the kidneys observed in high-dose multi-generational rat study; No evidence of mutagenicity, carcinogenicity, reproductive toxicity, or developmental toxicity; [EFSA]

Reference Link #1

Biomedical References

1.03E-13 mm Hg

LC50 (rat) > 5,700 mg/m3

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)