Triphenylphosphine oxide
Agent Name
Triphenylphosphine oxide
CAS Number
791-28-6
Formula
C18-H15-O-P
Major Category
Other Classes
Synonyms
Triphenyl phosphine oxide; Triphenyl phosphorus oxide; Phosphine oxide, triphenyl-; [ChemIDplus] Triphenylphosphine monoxide; [IUCLID]
Category
Phosphorus Compounds
Description
Solid; [IUCLID] Beige crystalline solid; [Aldrich MSDS]
Sources/Uses
Used for processing (extraction, separation, and spectrophotometric determination) environmental samples of cadmium and mercury; [ChemIDplus]
Comments
Causes convulsions, aggression, and dyspnea in oral lethal-dose studies of dogs (LD50 = 500 mg/kg); [RTECS] Causes liver injury in 3-month feeding study of dogs at 2,000 ppm; [IUCLID] An irritant; Harmful by ingestion; Targets nerves; [Aldrich MSDS] See "Triphenylphosphine."
Biomedical References
Exposure Assessment
Explanatory Notes
VP < 0.75 mm Hg at 50 deg C; [IUCLID]
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.