Major Category
Other Classes
Synonyms
1,3-Propanedial; 1,3-Propanedialdehyde; 1,3-Propanedione; Malondialdehyde; Malonic aldehyde; Malonic dialdehyde; Malonodialdehyde; Malonyldialdehyde; Propanedial; [ChemIDplus]
Description
Solid (needles); [NIOSH]
Sources/Uses
Used in scientific research; [HSDB] Produced during lipid peroxidation and other reactions in mammals; Used as index for rancidity in foods; [Merck Index] Found in many foods (at high levels if rancid); [IARC]
Comments
Evidence of injury to the liver and pancreas in mice experiments when added to drinking water at 500 mg/kg body weight per day; [HSDB] No listed effects of short-term or long-term exposure; [ICSC] May cause skin, eye, and respiratory tract irritation; Excessive exposure may cause CNS depression; [Merck Index] Causes muscle weakness, dyspnea, and cyanosis in oral lethal-dose study of rats; Causes other gastrointestinal and liver changes and inflammation, necrosis, or scarring of bladder in 90-day oral study of mice; [RTECS] See "ALDEHYDES"
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Not classifiable
Other Information
No other related information on this agent was found.