2,3-Dichloropropanol

Agent Name
2,3-Dichloropropanol
CAS Number
616-23-9
Formula
C3-H6-Cl2-O
Major Category
Other Classes
2,3-Dichloropropanol formula graphical representation
Synonyms
1,2-Dichloro-3-propanol; 1-Propanol, 2,3-dichloro-; 2,3-Dichloro-1-propanol; 2,3-Dichloropropyl alcohol; Glycerol 1,2-dichlorohydrin; Glycerol alpha,beta-dichlorohydrin; alpha,beta-Dichlorohydrin; 2,3-Dichloropropan-1-ol; [ChemIDplus] UN2750
Category
Halogenated Alcohols
Description
Colorless to amber liquid with an ethereal odor; [CAMEO]
Sources/Uses
Used for the production of epichlorohydrin; [HSDB]
Comments
Irritating to skin; Severely irritating to eyes; Poisonous by ingestion and skin contact; Moderately toxic by inhalation; "Two middle aged men developed severe hepatic injury just after cleaning a dichloropropanol tank at a plant producing dichloropropanol. They died from hepatic failure 4 and 11 days respectively, after carrying out the work. Liver specimens taken at autopsy from one of the cases showed submassive hepatic necrosis." [HSDB] Toxic after ingestion or skin absorption; An irritant; May cause serious injury to eyes; [MSDSonline]
Reference Link #1
Biomedical References

Exposure Assessment

Vapor Pressure
0.184 mm Hg
Lethal Concentration
LCLo (rat) = 500 ppm/4h
Explanatory Notes
VP from ChemIDplus;

Adverse Effects

Hepatotoxin
Occupational hepatotoxin (principal effect)

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: