Glycidyl methacrylate

Agent Name
Glycidyl methacrylate
CAS Number
106-91-2
Formula
C7-H10-O3
Major Category
Plastics & Rubber
Glycidyl methacrylate formula graphical representation
Synonyms
1-Propanol, 2,3-epoxy-, methacrylate; 2,3-Epoxypropyl methacrylate; 2,3-Epoxypropyl methacrylic acid ester; 2-((Methacryloxy)methyl)oxirane; 2-Propenoic acid, 2-methyl-, oxiranylmethyl ester; Acriester G; Blemmer G; Blemmer GMA; CP 105; Glycidol methacrylate; Glycidyl alpha-methyl acrylate; Glycidyl alpha-methylacrylate; Light Ester G; Methacrylic acid, 2,3-epoxypropyl ester; SR 379; SY-Monomer G; 2-Propenoic acid, 2-methyl-, 2-oxiranylmethyl ester; [ChemIDplus]
Category
(Meth)acrylates
Description
Colorless liquid with a fruity odor; [HSDB]
Sources/Uses
Chemical intermediate for polymers; monomer and diluent in epoxy resin formulations; [HSDB] Used in Japan as an intermediate for resins and other chemicals; Also used in emulsions for impregnating paper and textiles, in paint coatings, and adhesive applications; [OECD SIDS: Glycidyl methacrylate - 1999]
Comments
Allergic contact dermatitis reported in workers using anaerobic sealants; [Kanerva, p. 1741] Liquid causes first degree burns on short exposure. [CHRIS] Glycidyl methacrylate is a skin irritant. [Quick CPC] Causes labored breathing and corneal injuries in lethal concentration studies; [AIHA] May polymerize on exposure to heat or light; A severe skin, eye, and respiratory tract irritant; Can cause burns to skin and eyes; May cause skin sensitization; [ICSC] Reports of ACD in adhesive sealant manufacturing employees and one chemist; [OECD SIDS: Glycidyl methacrylate - 1999] Exposure to monomer is not expected in handling polymerized products; [IARC monograph volume 125]
Biomedical References

Exposure Assessment

Vapor Pressure
3.15 mm Hg
Lethal Concentration
LCLo (rat) = 1,400 mg/m3/6hr
Explanatory Notes
VP, kPa at 25 deg C: 0.42; [ICSC] See 2022 "Notice of Intended Changes" for TLV; [ACGIH TLVs and BEIs]
WEEL
0.5 ppm

Adverse Effects

Skin Sensitizer
Yes
Dermatotoxin
Skin burns
IARC Carcinogen
Probable (2a)

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: